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LncRNA Sox2OT-V7 promotes doxorubicin-induced autophagy and chemoresistance in osteosarcoma via tumor-suppressive miR-142/miR-22

Doxorubicin (Dox) is one of the most commonly used chemotherapeutic drugs for osteosarcoma (OS) treatment. In the present study, we attempted to investigate the mechanism by which Sox2OT-V7 dysregulation affects Dox chemoresistance to provide a novel experimental basis for developing neoadjuvant the...

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Bibliografiske detaljer
Udgivet i:Aging (Albany NY)
Main Authors: Zhu, Kewei, Yuan, Yang, Wen, Jie, Chen, Ding, Zhu, Weihong, Ouyang, Zhengxiao, Wang, Wanchun
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202483/
https://ncbi.nlm.nih.gov/pubmed/32302291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103004
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