Conditional knockout of kisspeptin signaling in brown adipose tissue increases metabolic rate and body temperature and lowers body weight

The peptide kisspeptin and its receptor, Kiss1r, act centrally to stimulate reproduction. Evidence indicates that kisspeptin signaling is also important for body weight (BW) and metabolism. We recently reported that Kiss1r KO mice develop obesity, along with reduced metabolism and energy expenditure...

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Vydáno v:FASEB J
Hlavní autoři: Tolson, Kristen P., Marooki, Nuha, De Bond, Julie-Ann P., Walenta, Evelyn, Stephens, Shannon B.Z., Liaw, Reanna B., Savur, Rishi, Wolfe, Andrew, Oh, Da Young, Smith, Jeremy T., Kauffman, Alexander S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202476/
https://ncbi.nlm.nih.gov/pubmed/31914628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901600R
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