Submicromolar copper (II) ions stimulate transretinal signaling in the isolated retina from wild type but not from Ca(v)2.3-deficient mice

BACKGROUND: So far, only indirect evidence exists for the pharmacoresistant R-type voltage-gated Ca(2+) channel (VGCC) to be involved in transretinal signaling by triggering GABA-release onto ON-bipolar neurons. This release of inhibitory neurotransmitters was deduced from the sensitivity of the b-w...

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Detalles Bibliográficos
Publicado en:BMC Ophthalmol
Main Authors: Lüke, Jan Niklas, Neumaier, Felix, Alpdogan, Serdar, Hescheler, Jürgen, Schneider, Toni, Albanna, Walid, Akhtar-Schäfer, Isha
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201970/
https://ncbi.nlm.nih.gov/pubmed/32375703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12886-020-01451-8
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