Intratumoral accumulation of gut microbiota facilitates CD47-based immunotherapy via STING signaling

Most studies focus on how intestinal microbiota influence cancer immunotherapy through activating gut immunity. However, immunotherapies related to innate responses such as CD47 blockade rely on the rapid immune responses within the tumor microenvironment. Using one defined anaerobic gut microbiota...

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Detalles Bibliográficos
Publicado en:J Exp Med
Main Authors: Shi, Yaoyao, Zheng, Wenxin, Yang, Kaiting, Harris, Katharine G., Ni, Kaiyuan, Xue, Lai, Lin, Wenbin, Chang, Eugene B., Weichselbaum, Ralph R., Fu, Yang-Xin
Formato: Artigo
Idioma:Inglês
Publicado: Rockefeller University Press 2020
Assuntos:
Brief Definitive Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201921/
https://ncbi.nlm.nih.gov/pubmed/32142585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20192282
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