A carregar...
Phosphorylated Lamin A/C in the nuclear interior binds active enhancers associated with abnormal transcription in progeria
LMNA encodes nuclear Lamin A/C that tethers lamina-associated domains (LADs) to the nuclear periphery. Mutations in LMNA cause degenerative disorders including the premature aging disorder Hutchinson-Gilford progeria, but the mechanisms are unknown. We report that Ser22-phosphorylated (pS22) Lamin A...
Na minha lista:
| Publicado no: | Dev Cell |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7201903/ https://ncbi.nlm.nih.gov/pubmed/32208162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.02.011 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|