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Depressed neuromuscular transmission causes weakness in mice lacking BK potassium channels

Mice lacking functional large-conductance voltage- and Ca(2+)-activated K(+) channels (BK channels) are viable but have motor deficits including ataxia and weakness. The cause of weakness is unknown. In this study, we discovered, in vivo, that skeletal muscle in mice lacking BK channels (BK(−/−)) wa...

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Detalhes bibliográficos
Publicado no:J Gen Physiol
Main Authors: Wang, Xueyong, Burke, Steven R.A., Talmadge, Robert J., Voss, Andrew A., Rich, Mark M.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201880/
https://ncbi.nlm.nih.gov/pubmed/32243496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201912526
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