Generation of Cellular Reactive Oxygen Species by Activation of the EP2 Receptor Contributes to Prostaglandin E2-Induced Cytotoxicity in Motor Neuron-Like NSC-34 Cells

Amyotrophic lateral sclerosis (ALS) is a devastating motor neuron disease characterized by progressive degeneration of motor neurons in the central nervous system. Prostaglandin E2 (PGE2) plays a pivotal role in the degeneration of motor neurons in human and transgenic models of ALS. We have shown p...

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Bibliografiska uppgifter
I publikationen:Oxid Med Cell Longev
Huvudupphovsmän: Kosuge, Yasuhiro, Nango, Hiroshi, Kasai, Hiroki, Yanagi, Takuya, Mawatari, Takayuki, Nishiyama, Kenta, Miyagishi, Hiroko, Ishige, Kumiko, Ito, Yoshihisa
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi 2020
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201578/
https://ncbi.nlm.nih.gov/pubmed/32411331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/6101838
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