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Hydroxymethylation and tumors: can 5-hydroxymethylation be used as a marker for tumor diagnosis and treatment?

5-Methylcytosine (5mC) is considered as a common epigenetic modification that plays an important role in the regulation of gene expression. At the same time, 5-hydroxymethylcytosine (5hmC) has been found as an emerging modification of cytosine bases of recent years. Unlike 5mC, global 5hmC levels va...

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Bibliographic Details
Published in:Hum Genomics
Main Authors: Xu, Tianmin, Gao, Haoyue
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201531/
https://ncbi.nlm.nih.gov/pubmed/32375881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-020-00265-5
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