Molecular Mechanisms of Trophoblast Dysfunction Mediated by Imbalance between STOX1 Isoforms

STOX1 is a transcription factor involved in preeclampsia and Alzheimer disease. We show that the knock-down of the gene induces rather mild effect on gene expression in trophoblast cell lines (BeWo). We identified binding sites of STOX1 shared by the two major isoforms, STOX1A and STOX1B. Profiling...

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Bibliografski detalji
Izdano u:iScience
Glavni autori: Ducat, Aurélien, Couderc, Betty, Bouter, Anthony, Biquard, Louise, Aouache, Rajaa, Passet, Bruno, Doridot, Ludivine, Cohen, Marie-Benoîte, Ribaux, Pascale, Apicella, Clara, Gaillard, Irène, Palfray, Sophia, Chen, Yulian, Vargas, Alexandra, Julé, Amélie, Frelin, Léo, Cocquet, Julie, San Martin, Camino Ruano, Jacques, Sébastien, Busato, Florence, Tost, Jorg, Méhats, Céline, Laissue, Paul, Vilotte, Jean-Luc, Miralles, Francisco, Vaiman, Daniel
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200942/
https://ncbi.nlm.nih.gov/pubmed/32371375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101086
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