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Transcriptional profiling of murine macrophages stimulated with cartilage fragments revealed a strategy for treatment of progressive osteoarthritis

Accumulating evidence suggests that synovitis is associated with osteoarthritic process. Macrophages play principal role in development of synovitis. Our earlier study suggests that interaction between cartilage fragments and macrophages exacerbates osteoarthritic process. However, molecular mechani...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Hamasaki, Masanari, Terkawi, Mohamad Alaa, Onodera, Tomohiro, Tian, Yuan, Ebata, Taku, Matsumae, Gen, Alhasan, Hend, Takahashi, Daisuke, Iwasaki, Norimasa
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200748/
https://ncbi.nlm.nih.gov/pubmed/32371954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64515-1
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