Allelic variants between mouse substrains BALB/cJ and BALB/cByJ influence mononuclear cardiomyocyte composition and cardiomyocyte nuclear ploidy

Most mouse cardiomyocytes (CMs) become multinucleated shortly after birth via endoreplication and interrupted mitosis, which persists through adulthood. The very closely related inbred mouse strains BALB/cJ and BALB/cByJ differ substantially (6.6% vs. 14.3%) in adult mononuclear CM level. This diffe...

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Publicado no:Sci Rep
Main Authors: Gan, Peiheng, Patterson, Michaela, Watanabe, Hirofumi, Wang, Kristy, Edmonds, Reilly A., Reinholdt, Laura G., Sucov, Henry M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200697/
https://ncbi.nlm.nih.gov/pubmed/32371981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64621-0
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