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Total Synthesis of Pyrolaside B: Phenol Trimerization via Sequenced Oxidative C-C and C-O Coupling

A facile method to oxidatively trimerize phenols using a low loading catalytic aerobic copper system is described. The mechanism of this transformation is probed, an understanding of which enabled cross coupling trimerizations. With this method, the natural product pyrolaside B has been synthesized...

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Bibliografiset tiedot
Julkaisussa:Angew Chem Int Ed Engl
Päätekijät: Neuhaus, William C., Kozlowski, Marisa C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200290/
https://ncbi.nlm.nih.gov/pubmed/32026544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201915654
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