Usefulness of Circulating Methylated p16 as a Noninvasive Molecular Biomarker for Hepatitis C-Related Hepatocellular Carcinoma with Normal Serum Alpha-Fetoprotein Levels

BACKGROUND: Screening of hepatocellular carcinoma (HCC) is challenged especially in patients with normal alpha-fetoprotein (AFP) levels. Aberrant p16 methylation has been implicated in HCC. OBJECTIVES AND AIMS: This study aimed to assess serum methylated p16 (MP16) expression levels and to evaluate...

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Détails bibliographiques
Publié dans:Int J Gen Med
Auteurs principaux: Elsewify, Wael Abd Elgwad, Hassan, Elham Ahmed, Mekky, Mohamed A, Abd El-Rehim, Abeer Sharaf El-Din, Sayed, Zain El-Abdeen Ahmed, Abdel Malek, Mohamed Omar, ElMelegy, Tarek T H, Sabry, Abeer
Format: Artigo
Langue:Inglês
Publié: Dove 2020
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200244/
https://ncbi.nlm.nih.gov/pubmed/32431531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJGM.S249272
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