Preferences to receive unsolicited findings of germline genome sequencing in a large population of patients with cancer

BACKGROUND: In precision medicine, somatic and germline DNA sequencing are essential to make genome-guided treatment decisions in patients with cancer. However, it can also uncover unsolicited findings (UFs) in germline DNA that could have a substantial impact on the lives of patients and their rela...

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Veröffentlicht in:ESMO Open
Hauptverfasser: Bijlsma, Rhode, Wouters, Roel, Wessels, Hester, Sleijfer, Stefan, Beerepoot, Laurens, ten Bokkel Huinink, Daan, Cruijsen, Hester, Heijns, Joan, Lolkema, Martijn P, Steeghs, Neeltje, van Voorthuizen, Theo, Vulink, Annelie, Witteveen, Els, Ausems, Margreet, Bredenoord, Annelien, May, Anne M, Voest, Emile
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2020
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200077/
https://ncbi.nlm.nih.gov/pubmed/32312756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/esmoopen-2019-000619
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