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Mitochondrial fragmentation enables localized signaling required for cell repair

Plasma membrane injury can cause lethal influx of calcium, but cells survive by mounting a polarized repair response targeted to the wound site. Mitochondrial signaling within seconds after injury enables this response. However, as mitochondria are distributed throughout the cell in an interconnecte...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Horn, Adam, Raavicharla, Shreya, Shah, Sonna, Cox, Dan, Jaiswal, Jyoti K.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199862/
https://ncbi.nlm.nih.gov/pubmed/32236517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201909154
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