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Targeting the oncogenic activity of TCF3-HLF in leukemia
The oncogenic fusion transcription factor TCF3-HLF identifies an aggressive subtype of acute lymphoblastic leukemia. TCF3-HLF imposes a malignant program by activation of lineage-specific oncogenic enhancers. Among critical cofactors of the TCF3-HLF complex we identified EP300, which functional inhi...
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| Published in: | Mol Cell Oncol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7199759/ https://ncbi.nlm.nih.gov/pubmed/32391417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2019.1709391 |
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