Targeting Ubiquitin-Proteasome Pathway by Natural Products: Novel Therapeutic Strategy for Treatment of Neurodegenerative Diseases

Misfolded proteins are the main common feature of neurodegenerative diseases, thereby, normal proteostasis is an important mechanism to regulate the neural survival and the central nervous system functionality. The ubiquitin-proteasome system (UPS) is a non-lysosomal proteolytic pathway involved in...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Momtaz, Saeideh, Memariani, Zahra, El-Senduny, Fardous F., Sanadgol, Nima, Golab, Fereshteh, Katebi, Majid, Abdolghaffari, Amir Hossein, Farzaei, Mohammad Hosein, Abdollahi, Mohammad
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199656/
https://ncbi.nlm.nih.gov/pubmed/32411012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00361
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