Sickle Cell Anemia Patients Display an Intricate Cellular and Serum Biomarker Network Highlighted by TCD4+CD69+ Lymphocytes, IL-17/MIP-1β, IL-12/VEGF, and IL-10/IP-10 Axis

BACKGROUND: Sickle cell anemia (SCA) is associated with a chronic proinflammatory state characterized by elevated leukocyte count, mortality from severe recurrent infections, and subsequent vasoocclusive complications with leukocyte adhesion to the endothelium and increased plasma levels of inflamma...

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Vydáno v:J Immunol Res
Hlavní autoři: Garcia, Nadja Pinto, Júnior, Alexander Leonardo S., Soares, Geyse Adriana S., Costa, Thainá Cristina C., dos Santos, Alicia Patrine C., Costa, Allyson Guimarães, Tarragô, Andréa Monteiro, Martins, Rejane Nina, do Carmo Leão Pontes, Flávia, de Almeida, Emerson Garcia, de Paula, Erich Vinícius, Martins-Filho, Olindo Assis, Malheiro, Adriana
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199620/
https://ncbi.nlm.nih.gov/pubmed/32411797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4585704
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