Low Expression of Programmed Death 1 (PD-1), PD-1 Ligand 1 (PD-L1), and Low CD8+ T Lymphocyte Infiltration Identify a Subgroup of Patients With Gastric and Esophageal Adenocarcinoma With Severe Prognosis

Prognosis of gastric and esophageal cancer is poor and treatment improvements are needed. Programmed cell death 1 receptor (PD-1) interaction with its ligand PD-L1 in tumor micro-environment promotes immune tolerance and blocking monoclonal antibodies have entered clinical practice. However, clinica...

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Detalhes bibliográficos
Publicado no:Front Med (Lausanne)
Main Authors: Däster, Silvio, Eppenberger-Castori, Serenella, Mele, Valentina, Schäfer, Hannah M., Schmid, Lukas, Weixler, Benjamin, Soysal, Savas D., Droeser, Raoul A., Spagnoli, Giulio C., Kettelhack, Christoph, Oertli, Daniel, Terracciano, Luigi, Tornillo, Luigi, von Holzen, Urs
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199486/
https://ncbi.nlm.nih.gov/pubmed/32411711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2020.00144
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