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Heterogeneous Nuclear Ribonucleoprotein L Negatively Regulates Foot-and-Mouth Disease Virus Replication through Inhibition of Viral RNA Synthesis by Interacting with the Internal Ribosome Entry Site in the 5′ Untranslated Region
Upon infection, the highly structured 5′ untranslated region (5′ UTR) of picornavirus is involved in viral protein translation and RNA synthesis. As a critical element in the 5′ UTR, the internal ribosome entry site (IRES) binds to various cellular proteins to function in the processes of picornavir...
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| Publicado no: | J Virol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7199413/ https://ncbi.nlm.nih.gov/pubmed/32161169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00282-20 |
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