Cholinergic Modulation of Disorder-Relevant Neural Circuits in Generalized Anxiety Disorder

BACKGROUND: Generalized anxiety disorder is associated with hyperactivity in the amygdala-prefrontal networks, and normalization of this aberrant function is thought to be critical for successful treatment. Preclinical evidence implicates cholinergic neurotransmission in the function of these system...

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Pubblicato in:Biol Psychiatry
Autori principali: Wise, Toby, Patrick, Fiona, Meyer, Nicholas, Mazibuko, Ndaba, Oates, Alice E., van der Bijl, Anne H.M., Danjou, Philippe, O’Connor, Susan M., Doolin, Elizabeth, Wooldridge, Caroline, Rathjen, Deborah, Macare, Christine, Williams, Steven C.R., Perkins, Adam, Young, Allan H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7198974/
https://ncbi.nlm.nih.gov/pubmed/32107005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2019.12.013
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