Tracking of an Oral Salmonella-Based Vaccine for Type 1 Diabetes in Non-obese Diabetic Mice

Type 1 diabetes (T1D) arises secondary to immune-driven destruction of pancreatic β-cells and manifests as insulin-deficient hyperglycemia. We showed that oral vaccination with live attenuated Salmonella, which simultaneously delivers autoantigens and a TGFβ expression vector to immune cells in the...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Mbongue, Jacques C., Alhoshani, Ali, Rawson, Jeffrey, Garcia, Pablo A., Gonzalez, Nelson, Ferreri, Kevin, Kandeel, Fouad, Husseiny, Mohamed I.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7198770/
https://ncbi.nlm.nih.gov/pubmed/32411136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00712
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