Non-esterified Fatty Acid Induce Dairy Cow Hepatocytes Apoptosis via the Mitochondria-Mediated ROS-JNK/ERK Signaling Pathway

Elevated plasma non-esterified fatty acid (NEFA) levels and hepatocytes damage are characteristics of ketosis in dairy cows. Oxidative stress is associated with the pathogenesis of NEFA-induced liver damage. However, the exact mechanism by which oxidative stress mediates NEFA-induced hepatocytes apo...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Li, Yu, Ding, Hongyan, Liu, Leihong, Song, Yuxiang, Du, Xiliang, Feng, Shibin, Wang, Xichun, Li, Xiaobing, Wang, Zhe, Li, Xinwei, Li, Jinchun, Wu, Jinjie, Liu, Guowen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7198733/
https://ncbi.nlm.nih.gov/pubmed/32411699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00245
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