Organoid-Transplant Model Systems to Study the Effects of Obesity on the Pancreatic Carcinogenesis in vivo

Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related mortality among adults in developed countries. The discovery of the most common genetic alterations as well as the development of organoid models of pancreatic cancer have provided insight into the fundamental pathw...

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Dettagli Bibliografici
Pubblicato in:Front Cell Dev Biol
Autori principali: Lupo, Francesca, Piro, Geny, Torroni, Lorena, Delfino, Pietro, Trovato, Rosalinda, Rusev, Borislav, Fiore, Alessandra, Filippini, Dea, De Sanctis, Francesco, Manfredi, Marcello, Marengo, Emilio, Lawlor, Rita Teresa, Martini, Maurizio, Tortora, Giampaolo, Ugel, Stefano, Corbo, Vincenzo, Melisi, Davide, Carbone, Carmine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Cell and Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7198708/
https://ncbi.nlm.nih.gov/pubmed/32411709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00308
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