Immunoevolution of mouse pancreatic organoid isografts from preinvasive to metastatic disease

Pancreatic ductal adenocarcinoma (PDA) has a highly immunosuppressive microenvironment, which is contributed by the complex interaction between cancer cells and a heterogeneous population of stromal cells. Therefore, facile and trackable models are needed for integrative and dynamic interrogation of...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Filippini, Dea, Agosto, Sabrina D’, Delfino, Pietro, Simbolo, Michele, Piro, Geny, Rusev, Borislav, Veghini, Lisa, Cantù, Cinzia, Lupo, Francesca, Ugel, Stefano, De Sanctis, Francesco, Bronte, Vincenzo, Milella, Michele, Tortora, Giampaolo, Scarpa, Aldo, Carbone, Carmine, Corbo, Vincenzo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706454/
https://ncbi.nlm.nih.gov/pubmed/31439856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48663-7
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