Immunoevolution of mouse pancreatic organoid isografts from preinvasive to metastatic disease

Pancreatic ductal adenocarcinoma (PDA) has a highly immunosuppressive microenvironment, which is contributed by the complex interaction between cancer cells and a heterogeneous population of stromal cells. Therefore, facile and trackable models are needed for integrative and dynamic interrogation of...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Filippini, Dea, Agosto, Sabrina D’, Delfino, Pietro, Simbolo, Michele, Piro, Geny, Rusev, Borislav, Veghini, Lisa, Cantù, Cinzia, Lupo, Francesca, Ugel, Stefano, De Sanctis, Francesco, Bronte, Vincenzo, Milella, Michele, Tortora, Giampaolo, Scarpa, Aldo, Carbone, Carmine, Corbo, Vincenzo
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706454/
https://ncbi.nlm.nih.gov/pubmed/31439856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48663-7
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires