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Immunoevolution of mouse pancreatic organoid isografts from preinvasive to metastatic disease
Pancreatic ductal adenocarcinoma (PDA) has a highly immunosuppressive microenvironment, which is contributed by the complex interaction between cancer cells and a heterogeneous population of stromal cells. Therefore, facile and trackable models are needed for integrative and dynamic interrogation of...
Enregistré dans:
| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6706454/ https://ncbi.nlm.nih.gov/pubmed/31439856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48663-7 |
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