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Short Residence Times of DNA-Bound Transcription Factors Can Reduce Gene Expression Noise and Increase the Transmission of Information in a Gene Regulation System

Gene expression noise is not just ubiquitous but also variable, and we still do not understand some of the most elementary factors that affect it. Among them is the residence time of a transcription factor (TF) on DNA, the mean time that a DNA-bound TF remains bound. Here, we use a stochastic model...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Azpeitia, Eugenio, Wagner, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7198700/
https://ncbi.nlm.nih.gov/pubmed/32411721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.00067
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