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A Deleted Deletion Site in a New Vector Strain and Exceptional Genomic Stability of Plaque-Purified Modified Vaccinia Ankara (MVA)

Vectored vaccines based on highly attenuated modified vaccinia Ankara (MVA) are reported to be immunogenic, tolerant to pre-existing immunity, and able to accommodate and stably maintain very large transgenes. MVA is usually produced on primary chicken embryo fibroblasts, but production processes ba...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Virol Sin
Main Authors: Jordan, Ingo, Horn, Deborah, Thiele, Kristin, Haag, Lars, Fiddeke, Katharina, Sandig, Volker
פורמט: Artigo
שפה:Inglês
יצא לאור: Springer Singapore 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7198643/
https://ncbi.nlm.nih.gov/pubmed/31833037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12250-019-00176-3
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