Comprehensive aptamer-based screening identifies a spectrum of urinary biomarkers of lupus nephritis across ethnicities

Emerging urinary biomarkers continue to show promise in evaluating lupus nephritis (LN). Here, we screen urine from active LN patients for 1129 proteins using an aptamer-based platform, followed by ELISA validation in two independent cohorts comprised of 127 inactive lupus, 107 active LN, 67 active...

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Udgivet i:Nat Commun
Main Authors: Stanley, Samantha, Vanarsa, Kamala, Soliman, Samar, Habazi, Deena, Pedroza, Claudia, Gidley, Gabriel, Zhang, Ting, Mohan, Shree, Der, Evan, Suryawanshi, Hemant, Tuschl, Thomas, Buyon, Jill, Putterman, Chaim, Mok, Chi Chiu, Petri, Michelle, Saxena, Ramesh, Mohan, Chandra
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7198599/
https://ncbi.nlm.nih.gov/pubmed/32366845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15986-3
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