The limitations of targeting MEK signalling in Glioblastoma therapy

Glioblastoma (GB) is a highly aggressive, difficult to treat brain tumour. Successful treatment, consisting of maximal safe tumour de-bulking, followed by radiotherapy and treatment with the alkylating agent Temozolomide (TMZ), can extend patient survival to approximately 15 months. Combination trea...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Selvasaravanan, Karthika D., Wiederspohn, Nicole, Hadzalic, Amina, Strobel, Hannah, Payer, Christel, Schuster, Andrea, Karpel-Massler, Georg, Siegelin, Markus D., Halatsch, Marc-Eric, Debatin, Klaus-Michael, Westhoff, Mike-Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7198577/
https://ncbi.nlm.nih.gov/pubmed/32366879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64289-6
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