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SWATH-MS analysis of cerebrospinal fluid to generate a robust battery of biomarkers for Alzheimer’s disease

Cerebrospinal fluid (CSF) Aβ42 and tau protein levels are established diagnostic biomarkers of Alzheimer’s disease (AD). However, their inadequacy to represent clinical efficacy in drug trials indicates the need for new biomarkers. Sequential window acquisition of all theoretical fragment ion spectr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Park, Sun Ah, Jung, Jin Myung, Park, Jun Sung, Lee, Jeong Ho, Park, Bumhee, Kim, Hyung Jun, Park, Jeong-Ho, Chae, Won Seok, Jeong, Jee Hyang, Choi, Seong Hye, Baek, Je-Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7198522/
https://ncbi.nlm.nih.gov/pubmed/32366888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64461-y
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