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Differences in intracellular localisation of ANKH mutants that relate to mechanisms of calcium pyrophosphate deposition disease and craniometaphyseal dysplasia

ANKH mutations are associated with calcium pyrophosphate deposition disease and craniometaphyseal dysplasia. This study investigated the effects of these ANKH mutants on cellular localisation and associated biochemistry. We generated four ANKH overexpression-plasmids containing either calcium pyroph...

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Publicat a:Sci Rep
Autors principals: Vijen, Sunny, Hawes, Chris, Runions, John, Russell, R. Graham G., Wordsworth, B. Paul, Carr, Andrew J., Pink, Ryan C., Zhang, Yun
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7198517/
https://ncbi.nlm.nih.gov/pubmed/32366894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63911-x
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