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Differences in intracellular localisation of ANKH mutants that relate to mechanisms of calcium pyrophosphate deposition disease and craniometaphyseal dysplasia

ANKH mutations are associated with calcium pyrophosphate deposition disease and craniometaphyseal dysplasia. This study investigated the effects of these ANKH mutants on cellular localisation and associated biochemistry. We generated four ANKH overexpression-plasmids containing either calcium pyroph...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Vijen, Sunny, Hawes, Chris, Runions, John, Russell, R. Graham G., Wordsworth, B. Paul, Carr, Andrew J., Pink, Ryan C., Zhang, Yun
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7198517/
https://ncbi.nlm.nih.gov/pubmed/32366894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63911-x
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