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Increased O-GlcNAcylation rapidly decreases GABA(A)R currents in hippocampus but depresses neuronal output
O-GlcNAcylation, a post-translational modification involving O-linkage of β-N-acetylglucosamine to Ser/Thr residues on target proteins, is increasingly recognized as a critical regulator of synaptic function. Enzymes that catalyze O-GlcNAcylation are found at both presynaptic and postsynaptic sites,...
שמור ב:
| הוצא לאור ב: | Sci Rep |
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| Main Authors: | , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group UK
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7198489/ https://ncbi.nlm.nih.gov/pubmed/32366857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63188-0 |
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