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Emerging Pharmacological Targets for the Treatment of Nonalcoholic Fatty Liver Disease, Insulin Resistance, and Type 2 Diabetes

Type 2 diabetes (T2D) is characterized by persistent hyperglycemia despite hyperinsulinemia, affects more than 400 million people worldwide, and is a major cause of morbidity and mortality. Insulin resistance, of which ectopic lipid accumulation in the liver [nonalcoholic fatty liver disease (NAFLD)...

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Podrobná bibliografie
Vydáno v:Annu Rev Pharmacol Toxicol
Hlavní autoři: Goedeke, Leigh, Perry, Rachel J., Shulman, Gerald I.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7198260/
https://ncbi.nlm.nih.gov/pubmed/30625285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010716-104727
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