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MicroRNA-375 Targets ATG14 to Inhibit Autophagy and Sensitize Hepatocellular Carcinoma Cells to Sorafenib

PURPOSE: Sorafenib has revolutionized treatment of hepatocellular carcinoma (HCC), but its efficacy is limited by drug resistance. Autophagy is the process by which cellular components are transported to lysosomes for degradation, which promotes energy production and production of macromolecular pre...

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Publicat a:Onco Targets Ther
Autors principals: Yang, Shuo, Wang, Minggang, Yang, Liang, Li, Yan, Ma, Yingbo, Peng, Xueqiang, Li, Xinyu, Li, Bowen, Jin, Hongyuan, Li, Hangyu
Format: Artigo
Idioma:Inglês
Publicat: Dove 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197942/
https://ncbi.nlm.nih.gov/pubmed/32431510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S247655
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