The ubiquitin hydrolase Doa4 directly binds Snf7 to inhibit recruitment of ESCRT-III remodeling factors in S. cerevisiae

The ESCRT-III protein complex executes reverse-topology membrane scission. The scission mechanism is unclear but is linked to remodeling of ESCRT-III complexes at the membrane surface. At endosomes, ESCRT-III mediates the budding of intralumenal vesicles (ILVs). In Saccharomyces cerevisiae, ESCRT-II...

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Bibliographic Details
Published in:J Cell Sci
Main Authors: Buysse, Dalton, Pfitzner, Anna-Katharina, West, Matt, Roux, Aurélien, Odorizzi, Greg
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197871/
https://ncbi.nlm.nih.gov/pubmed/32184262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.241455
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