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Tocilizumab does not block interleukin-6 (IL-6) signaling in murine cells
Tocilizumab is a humanized monoclonal antibody that is approved for the treatment of different human inflammatory diseases, including rheumatoid arthritis and cytokine release syndrome. Tocilizumab binds to the interleukin-6 receptor (IL-6R) and thereby blocks signaling of the pro-inflammatory cytok...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7197771/ https://ncbi.nlm.nih.gov/pubmed/32365119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232612 |
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