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Disease Severity-Associated Gene Expression in Canine Myxomatous Mitral Valve Disease Is Dominated by TGFβ Signaling

Myxomatous mitral valve disease (MMVD) is the most common acquired canine cardiovascular disease and shares many similarities with human mitral valvulopathies. While transcriptomic datasets are available for the end-stage disease in both species, there is no information on how gene expression change...

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Publicado en:Front Genet
Autores principales: Markby, Greg R., Macrae, Vicky E., Summers, Kim M., Corcoran, Brendan M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197751/
https://ncbi.nlm.nih.gov/pubmed/32395121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00372
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