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Loss of Dmrt5 Affects the Formation of the Subplate and Early Corticogenesis

Dmrt5 (Dmrta2) and Dmrt3 are key regulators of cortical patterning and progenitor proliferation and differentiation. In this study, we show an altered apical to intermediate progenitor transition, with a delay in SP neurogenesis and premature birth of Ctip2(+) cortical neurons in Dmrt5(−/−) mice. In...

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Detalhes bibliográficos
Publicado no:Cereb Cortex
Main Authors: Ratié, Leslie, Desmaris, Elodie, García-Moreno, Fernando, Hoerder-Suabedissen, Anna, Kelman, Alexandra, Theil, Thomas, Bellefroid, Eric J, Molnár, Zoltán
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197206/
https://ncbi.nlm.nih.gov/pubmed/31845734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhz310
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