circNFIB1 inhibits lymphangiogenesis and lymphatic metastasis via the miR-486-5p/PIK3R1/VEGF-C axis in pancreatic cancer

BACKGROUND: Patients with lymph node (LN)-positive pancreatic ductal adenocarcinoma (PDAC) have extremely poor survival rates. Circular RNAs (circRNAs), a newly discovered type of endogenous noncoding RNAs, have been proposed to mediate the progression of diverse types of tumors. However, the role a...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Kong, Yao, Li, Yuting, Luo, Yuming, Zhu, Jiang, Zheng, Hanhao, Gao, Bowen, Guo, Xiaofeng, Li, Zhihua, Chen, Rufu, Chen, Changhao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197141/
https://ncbi.nlm.nih.gov/pubmed/32366257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-01205-6
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