FAT4 silencing promotes epithelial-to-mesenchymal transition and invasion via regulation of YAP and β-catenin activity in ovarian cancer

BACKGROUND: The adhesion molecule, FAT4, has a tumor suppressor function with a critical role in the epithelial-to-mesenchymal-transition (EMT) and anti-malignant growth in several cancers. No study has investigated yet its role in epithelial ovarian cancer (EOC) progression. In the present study, w...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Malgundkar, Shika Hanif, Burney, Ikram, Al Moundhri, Mansour, Al Kalbani, Moza, Lakhtakia, Ritu, Okamoto, Aikou, Tamimi, Yahya
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197128/
https://ncbi.nlm.nih.gov/pubmed/32366234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06900-7
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