Evolution of male pregnancy associated with remodeling of canonical vertebrate immunity in seahorses and pipefishes

A fundamental problem for the evolution of pregnancy, the most specialized form of parental investment among vertebrates, is the rejection of the nonself-embryo. Mammals achieve immunological tolerance by down-regulating both major histocompatibility complex pathways (MHC I and II). Although pregnan...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Roth, Olivia, Solbakken, Monica Hongrø, Tørresen, Ole Kristian, Bayer, Till, Matschiner, Michael, Baalsrud, Helle Tessand, Hoff, Siv Nam Khang, Brieuc, Marine Servane Ono, Haase, David, Hanel, Reinhold, Reusch, Thorsten B. H., Jentoft, Sissel
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2020
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196912/
https://ncbi.nlm.nih.gov/pubmed/32284407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1916251117
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