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Robust landscapes of ribosome dwell times and aminoacyl-tRNAs in response to nutrient stress in liver

Translation depends on messenger RNA (mRNA)-specific initiation, elongation, and termination rates. While translation elongation is well studied in bacteria and yeast, less is known in higher eukaryotes. Here we combined ribosome and transfer RNA (tRNA) profiling to investigate the relations between...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Gobet, Cédric, Weger, Benjamin Dieter, Marquis, Julien, Martin, Eva, Neelagandan, Nagammal, Gachon, Frédéric, Naef, Felix
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196831/
https://ncbi.nlm.nih.gov/pubmed/32295881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1918145117
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