Vip1 is a kinase and pyrophosphatase switch that regulates inositol diphosphate signaling

Inositol diphosphates (PP-IPs), also known as inositol pyrophosphates, are high-energy cellular signaling codes involved in nutrient and regulatory responses. We report that the evolutionarily conserved gene product, Vip1, possesses autonomous kinase and pyrophosphatase domains capable of synthesis...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Dollins, D. Eric, Bai, Wenli, Fridy, Peter C., Otto, James C., Neubauer, Julie L., Gattis, Samuel G., Mehta, Kavi P. M., York, John D.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196807/
https://ncbi.nlm.nih.gov/pubmed/32303658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1908875117
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