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EGFR‐targeted CAR‐T cells are potent and specific in suppressing triple‐negative breast cancer both in vitro and in vivo

OBJECTIVES: Triple‐negative breast cancer (TNBC) is well known for its strong invasiveness, rapid recurrence and poor prognosis. Immunotherapy, including chimeric antigen receptor‐modified T (CAR‐T) cells, has emerged as a promising tool to treat TNBC. The identification of a specific target tumor a...

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Detalhes bibliográficos
Publicado no:Clin Transl Immunology
Main Authors: Xia, Lin, Zheng, Zao‐zao, Liu, Jun‐yi, Chen, Yu‐jie, Ding, Jian‐cheng, Xia, Ning‐shao, Luo, Wen‐xin, Liu, Wen
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196685/
https://ncbi.nlm.nih.gov/pubmed/32373345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1135
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