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Atomic force microscopy–based characterization of the interaction of PriA helicase with stalled DNA replication forks

In bacteria, the restart of stalled DNA replication forks requires the DNA helicase PriA. PriA can recognize and remodel abandoned DNA replication forks, unwind DNA in the 3′-to-5′ direction, and facilitate the loading of the helicase DnaB onto the DNA to restart replication. Single-stranded DNA–bin...

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Pubblicato in:J Biol Chem
Autori principali: Wang, Yaqing, Sun, Zhiqiang, Bianco, Piero R., Lyubchenko, Yuri L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196660/
https://ncbi.nlm.nih.gov/pubmed/32209655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013013
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