Delineating an extracellular redox-sensitive module in T-type Ca(2+) channels

T-type (Cav3) Ca(2+) channels are important regulators of excitability and rhythmic activity of excitable cells. Among other voltage-gated Ca(2+) channels, Cav3 channels are uniquely sensitive to oxidation and zinc. Using recombinant protein expression in HEK293 cells, patch clamp electrophysiology,...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Huang, Dongyang, Shi, Sai, Liang, Ce, Zhang, Xiaoyu, Du, Xiaona, An, Hailong, Peers, Chris, Zhang, Hailin, Gamper, Nikita
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Molecular Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196644/
https://ncbi.nlm.nih.gov/pubmed/32188693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012668
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