NAD(+) biosynthesis in bacteria is controlled by global carbon/nitrogen levels via PII signaling

NAD(+) is a central metabolite participating in core metabolic redox reactions. The prokaryotic NAD synthetase enzyme NadE catalyzes the last step of NAD(+) biosynthesis, converting nicotinic acid adenine dinucleotide (NaAD) to NAD(+). Some members of the NadE family use l-glutamine as a nitrogen do...

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Pubblicato in:J Biol Chem
Autori principali: Santos, Adrian Richard Schenberger, Gerhardt, Edileusa Cristina Marques, Parize, Erick, Pedrosa, Fabio Oliveira, Steffens, Maria Berenice Reynaud, Chubatsu, Leda Satie, Souza, Emanuel Maltempi, Passaglia, Luciane Maria Pereira, Sant'Anna, Fernando Hayashi, de Souza, Gustavo Antônio, Huergo, Luciano Fernandes, Forchhammer, Karl
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2020
Soggetti:
Enzymology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196632/
https://ncbi.nlm.nih.gov/pubmed/32179648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012793
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