PAN-CANCER EFFICACY OF VEMURAFENIB IN BRAF(V600)-MUTANT NON-MELANOMA CANCERS

BRAF V600 mutations occur in a wide range of tumor types and RAF inhibition has become standard in several of these cancers. Despite this progress, BRAF V600 mutations have historically been considered a clear demonstration of tumor lineage context-dependent oncogene addiction, based predominantly o...

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Pubblicato in:Cancer Discov
Autori principali: Subbiah, Vivek, Puzanov, Igor, Blay, Jean-Yves, Chau, Ian, Lockhart, A. Craig, Raje, Noopur S., Wolf, Juergen, Baselga, Jose, Meric-Bernstam, Funda, Roszik, Jason, Diamond, Eli L., Riely, Gregory J., Sherman, Eric J., Riehl, Todd, Pitcher, Bethany, Hyman, David M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196502/
https://ncbi.nlm.nih.gov/pubmed/32029534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-19-1265
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