Heritable modifiers of the tumor microenvironment influence nanoparticle uptake, distribution and response to photothermal therapy

We report the impact of notch-DLL4-based hereditary vascular heterogeneities on the enhanced permeation and retention (EPR) effect and plasmonic photothermal therapy response in tumors. Methods: We generated two consomic rat strains with differing DLL4 expression on 3(rd) chromosome. These strains w...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Sharma, Gayatri, Jagtap, Jaidip M., Parchur, Abdul K., Gogineni, Venkateswara R., Ran, Sophia, Bergom, Carmen, White, Sarah B., Flister, Michael J., Joshi, Amit
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196309/
https://ncbi.nlm.nih.gov/pubmed/32373218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.41171
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