Selective delivery of T22-PE24-H6 to CXCR4(+) diffuse large B-cell lymphoma cells leads to wide therapeutic index in a disseminated mouse model

Background: Novel therapeutic strategies are urgently needed to reduce relapse rates and enhance survival in Diffuse Large B-Cell Lymphoma (DLBCL) patients. CXCR4-overexpressing cancer cells are good targets for therapy because of their association with dissemination and relapse in R-CHOP treated DL...

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Vydáno v:Theranostics
Hlavní autoři: Falgàs, Aïda, Pallarès, Victor, Serna, Naroa, Sánchez-García, Laura, Sierra, Jorge, Gallardo, Alberto, Alba-Castellón, Lorena, Álamo, Patricia, Unzueta, Ugutz, Villaverde, Antonio, Vázquez, Esther, Mangues, Ramon, Casanova, Isolda
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196303/
https://ncbi.nlm.nih.gov/pubmed/32373205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.43231
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